How do statins contribute to cardiac health?

Statins play a significant role in cardiac health primarily by lowering cholesterol levels and stabilizing atherosclerotic plaque in the arteries.

By inhibiting the HMG-CoA reductase enzyme, statins reduce the liver's production of cholesterol, leading to lower levels of low-density lipoprotein (LDL) cholesterol in the bloodstream. High levels of LDL are associated with the development of atherosclerosis, where plaques build up in the arteries. These plaques can become unstable and rupture, potentially leading to acute cardiovascular events like heart attacks. Statins not only help reduce the formation of new plaques but also stabilize existing plaques, making them less likely to rupture.

This dual action enhances overall cardiovascular health by reducing the risk of heart disease and improving outcomes in patients with existing cardiovascular conditions. The other options, while related to heart function and health in other contexts, do not accurately describe the primary mechanisms through which statins provide benefits.