Which ECG leads are primarily associated with the anterior wall of the heart?

The anterior wall of the heart is primarily perfused by the left anterior descending (LAD) artery, and the ECG leads that reflect electrical activity occurring in this region are V1 through V4.

Leads V1 and V2 are positioned close to the interventricular septum, while V3 and V4 are located on the anterior wall of the left ventricle. When assessing for conditions such as ischemia or infarction in the anterior wall, these leads provide critical information about any changes in the electrical activity that may indicate a problem like a blockage in the LAD artery.

In contrast, other sets of leads like II, III, and aVF focus on the inferior aspects of the heart, while leads I and aVL concentrate on the lateral wall. The frontal plane leads refer broadly to the leads in the frontal plane, which include I, II, III, aVR, aVL, and aVF, but they do not isolate the anterior wall specifically. Thus, V1-V4 is the definitive choice for assessing the anterior wall involvement on an ECG.